,

Can Alzheimer’s Be Reversed?

when alzheimers was first discovered

Can Alzheimer’s Be Reversed?

There have been recent developments that suggest that there is a possibility of reversing the memory loss that occurs in Alzheimer’s disease.  This is with the help of drugs which selectively block the ability of the HDAC2 enzyme to interfere with the communication between brain cells.

There is a binding molecule known as SP3 which binds to HDAC2 and when this molecule is blocked, they can both be stopped from disrupting synaptic function or the communication between brain cells important for memory.

HDAC2 affects memory by altering the proteins that help to package DNA into chromatin and HDAC2 particularly blocks some genes important for memory. There are higher levels of HDAC2 in Alzheimer’s patients.

So the targeting enzyme will work by selectively blocking the HDAC2 enzyme and the molecule sp3 to reverse any memory loss from Alzheimer’s.

There have also been studies into a treatment known as metabolic enhancement for neuro-degeneration or MEND. This treatment is based on 36 different factors including diet, exercise, sleeping habits, drugs, vitamins and brain stimulation therapy. This treatment shows promise in reversing memory loss from Alzheimer’s.

In another study by Cleveland Clinic Lerner Research Institute, clinical trials on mice have found that gradually depleting an enzyme known as BACE1 completely reverses the formation of amyloid plaques in the brains of the mice with Alzheimer’s. Hopefully, drugs targeting this enzyme will be able to successfully treat Alzheimer’s in humans as well.

It is indeed true that the memory loss from Alzheimer’s may be reversed. The future looks bright for the development of a cure.

Devoted Guardians – A Phoenix, AZ Based Home Care Company

We help people with Alzheimer’s. It is one of the main reasons seniors end up asking for assistance around the home.

We provide a level of personalized care and specialized services that are simply unmatched in Arizona. You can rest assured that our caregivers undergo an intensive screening process, and are equipped to provide quality home care services for individuals struggling to cope with a wide variety of illnesses, injuries, physical disabilities, and mental health issues ranging from dementia to Alzheimer’s.

Pinterest
LinkedIn

Leave a Comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Previous Post

How Will Alzheimer’s Affect The Future?

Next Post

Can Alzheimer’s Be Genetically Passed Down?

Devoted Guardians'
Response to COVID-19

Devoted Guardians is actively monitoring the progression of the coronavirus, COVID-19, to ensure that we have the most accurate and latest information on the threat of the virus. As you know, this situation continues to develop rapidly as new cases are identified in our communities and our protocols will be adjusted as needed.

While most cases of COVID-19 are mild, causing only fever and cough, a very small percentage of cases become severe and may progress particularly in the elderly and people with underlying medical conditions. Because this is the primary population that Devoted Guardians serves, we understand your concerns and want to share with you how our organization is responding to the threat of COVID-19.

We are following updates and procedures from the Centers for Disease Control (CDC) State Department of Health, local and county authorities, the Home Care Association of America and other agencies and resources. Our response and plans may adjust according to the recommendations from these organizations.